How To Get Insurance To Cover Botox For Migraines?

It’s vital to remember that most insurance companies will only pay Botox treatments if you’ve already tried and failed two other migraine treatments. They may require you to file a prior authorization form with your healthcare physician to confirm this.

Is Botox for migraine covered by insurance?

In general, each treatment at the FDA-recommended dosage of 155 units costs between $300 and $600. Botox is covered by most insurance plans, including Medicare and Medicaid, because it is FDA approved for chronic migraines. Allergan offers a “Botox Savings Card,” which allows patients to save money on their Botox treatments.

Please keep in mind that in order for your insurance company to accept Botox as a treatment for your chronic migraine, you must normally have tried and failed two other preventative therapies. Anti-seizure drugs, antidepressants, and blood pressure meds are examples of migraine-prevention medications.

How do you qualify for Botox for migraines?

Botox is only suggested for chronic migraine sufferers who meet the following criteria: More than 15 days of headaches every month, with at least 8 days of migraines lasting at least 4 hours each. For at least three months, struggle with the aforementioned. You must be at least 18 years old to participate.

Can Botox be billed to insurance?

Under FDA permission, most health insurance plans cover medical Botox therapy. Each treatment usually costs between $300 and $600 for a dosage of 155 units.

Is Botox for migraines the same as cosmetic Botox?

Here are some frequently asked questions about Botox’s use in adults with chronic migraines to prevent headaches.

Botox isn’t likely to help with wrinkles if you’re using it to prevent headaches from a chronic migraine.

Wrinkles are treated with a separate drug called Botox Cosmetic. Botox Cosmetic has the same active ingredient as Botox (onabotulinumtoxinA), but at a lower dose. Botox Cosmetic is injected in different injection sites to correct wrinkles than it is to prevent headaches.

Botox only affects the nerves in the muscle groups into which it is administered. As a result, Botox injections for headache relief are unlikely to alter wrinkles.

Consult your doctor if you have any inquiries about Botox for headaches or Botox Cosmetic for wrinkles.

What can I expect when I receive Botox injections for migraine?

Botox injections to prevent headaches in individuals with chronic migraines are typically safe, but they can have minor adverse effects. See the for more information “See the “Botox side effects” section above for additional information. You can also have a look at the “Talk to your doctor about receiving Botox injections, as described in the “Getting Botox Injections” section above.

What is the success rate of Botox for migraines?

In patients with chronic migraine, a response rate of 65 percent is estimated following three cycles of treatment with onabotulinumtoxin A (Botox). Long-term treatment with onabotulinumtoxin A is now efficacious, safe, and well-tolerated in the patient group, according to a new study.

The study researchers assessed onabotulinumtoxin A in patients who responded to the treatment after three sessions, building on a previous study that demonstrated the treatment’s short-term efficacy (it’s given every three months). The prospective, open-label, single-arm trial tracked patients at five headache centers across Greece.

“We previously observed that three courses of onabotulinumtoxin A preventive medication effectively reduced both the mean headache days/month and the days with peak headache intensity >4/10 in a sample of 81 patients, relative to baseline,” the researchers said. “There was also a decrease in the number of severe headache drugs taken each month.”

Does Botox for migraines cause weight gain?

One of the most significant benefits of Botox is that it does not produce the grogginess, nausea, weight gain, or other side effects that many oral preventative drugs do.

What next if Botox doesn’t work for migraines?

“The CGRP antagonists—Aimovig, Ajovy, and Emgality—would be good possibilities for people who cannot receive Botox presently owing to COVID-19,” says prominent migraine expert and Cove Medical Director Dr. Sara Crystal when working with your doctor to decide what to try next.

Is there a CPT code for Botox?

Botulinum toxin (BTX) therapy is becoming increasingly popular among clinicians. Unfortunately, even after a doctor has mastered the art of neurotoxic injection, billing and coding can be intimidating. For successful integration of botulinum toxin therapy into clinical practice, accurate coding using current procedural terminology (CPT) and International Classification of Diseases, Ninth Revision (ICD-9) linkage is essential. Clinicians must be knowledgeable with the purchase and storage of BTX, prior authorization needs across insurers, and proper procedural documentation in addition to understanding and using correct billing and coding. What needs to be done once a clinically acceptable patient has been identified in order to deliver timely, compensated treatment?

PRIOR AUTHORIZATION

Botulinum toxin treatment is covered by Medicare, Medicaid, and private insurance for medically essential on- and off-label usage. Many off-label treatments (for example, for lower limb spasticity or limb dystonia) are nevertheless deemed standard of care and will be approved. While Medicare policies differ by state, private insurance plans are generally universal. When it comes to filing for permission, knowing your state’s policies might save you time and frustration.

No prior permission is required for BTX under standard Medicare or Medicaid, and payment will be made if the operation is covered under your state’s policy and the necessary linkage between ICD-9 and CPT codes has been demonstrated. Even for on-label injections, all private insurances and Health Maintenance Organization (HMO) Medicare/Medicaid patients to be pre-approved for BTX. Prior authorization services provided by the toxic firm can speed up approvals and save time for workers. To authorize the company to contact their insurance provider, patients must sign a consent letter. Prior authorization requests should always include an office note supporting the need for BTX treatment as well as a letter of medical necessity (LMN). The desired toxin, ICD-9 diagnosis, previous treatment failures, projected quantity of vials, CPT codes, and electromyography or other guidance technique to be employed should all be included in the LMN.

First, benefits verification is done to ensure that the patient’s insurance policy is up to date and that it covers injectable treatments like BTX. Preapproval or medical necessity are not synonymous with benefit verification. Prior authorization is required to maximize the likelihood of timely payment. Most insurance companies will approve a patient for six to twelve months or two to four treatments if they have a prior authorization. Payment may be rejected if injections are not conducted within this authorized timeframe. Depending on the toxic firm, authorization can be submitted online or via fax. The estimated deductible depending on the patient’s plan is usually included in the authorization results, along with approved dates of service and approved CPT codes. The maximum number of toxin units allowed and how the medicine was obtained (i.e. buy and bill vs specialist pharmacy) are also listed.

ORDERING, STORAGE, AND BILLING THE TOXIN

Purchase from a specialized pharmacy or buy and bill by the practice are two options for obtaining the medicine. The clinic will be required to purchase and charge the medicine by Medicare and most private insurance companies. United Health Care, for example, requires the use of a third-party specialized pharmacy. The use of a specialized pharmacy can lessen the chance of losing money due to insurance denials, but it also lowers total reimbursement. A margin above the medicine’s cost is obtained if the physician obtains the drug and bills from his or her stock. The Medicare profit margin is 6% above the drug’s typical wholesale cost. Typically, private insurance companies reimburse between 6% and 20% more than the wholesale cost. Botox and Xeomin are invoiced in one-unit increments, Dysport is paid in five-unit increments, and Myobloc is billed in 100-unit increments. Remember to charge for both the amount of drug utilized for injection and the amount of drug squandered. For example, if a 200-unit vial of Botox is blended with 155-units to inject a patient with chronic migraine, the 45-units wasted are invoiced as well.

Companies differ in terms of toxin samples, discounts, and patient assistance programs. For specific company services, contact your local pharmaceutical agent. Each poison can be ordered directly from the manufacturer and should arrive the next day. When ordering items that require refrigeration, avoid arranging orders that could come on the weekend. All of the toxins should be kept together in a sealed refrigerator between 2 and 8 degrees Celsius with a temperature alarm. To ensure proper storage, have the drug transported straight to your office instead of the patient’s house when using a specialty pharmacy. With documentation of lot numbers, a separate log for drugs obtained by the practice and another for drugs obtained from specialized pharmacies is recommended. Inventory reconciliation on a weekly or monthly basis is also recommended. Table 1 lists the prices for each toxin, vial size, and billing J-Code.

PROCEDURE CODING, DOCUMENTATION, AND BILLING

For accurate payouts, proper paperwork is required. A dictated note with specifics such as the injection site and location, dilution, electrophysiologic/ultrasound guidance, medicine provider, and insurer approved dates of service and prior authorization number is recommended. Insurance companies prefer to see a documented process note with a graphic of the locations injected and an outline of the particular dosages given at each site, however it is not required. From a clinical standpoint, this makes subsequent injection replication easier. The toxin’s national drug code, which can be located on the vial or container, is also required by Medicaid.

It is not recommended to utilize an evaluation and management (E/M) code in conjunction with the BTX method. Only if a distinct identifiable medical service is offered for a different diagnosis than the one used for BTX is this classification appropriate. An E/M with a -25 modifier could be employed, for example, if a patient with Parkinson’s Disease (PD) was seen for both medical care of PD and BTX for sialorrhea. To ensure proper reimbursement, the medical diagnosis must be linked to the E/M and the other diagnostic (in this case, sialorrhea) must be related to the CPT code.

CPT Codes for Chemodenervation. The appropriate anatomic location “site” injected determines the specific chemodenervation codes for BTX. A complete list of chemodenervation codes and anatomic locales can be found in table 2. The Centers for Medicare and Medicaid Services will pay for one injection per site, regardless of how many injections are given. Use CPT 64611 to inject into the parotid and/or submandibular glands for sialorrhea. With no modifier, use only once. Any injection in the cranium (64612) is classified head/face, including the corregator, frontalis, temporalis, occipitalis, facial muscles, and masseter. The RT and LT modifiers, as well as the 50 modifier, can be used bilaterally with this code. Despite the fact that injections are performed in the cervical paraspinals and trapezii, all injections in the chronic migraine paradigm are considered one site (64515). There are no modifiers allowed. Both 64613 (neck injection) and 64614 (limb/trunk injection) have been removed off the market and will not be available in 2014. Both axillas are treated as a single site (64640 chemodenervaton of eccrine glands) and can be utilized only once per session. When injecting for hyperhidrosis in other locations such as the scalp, face, or extremities, use 64643, chemodenervaton of eccrine glands; other area(s).

2014 Codes are now available. Use the new code 64616 (chemodenervation of neck muscle(s) excluding muscles of the larynx) when injecting neck muscle for disorders such cervical dystonia. With a 50 modifier, this code can be billed bilaterally. Chemodenervation of one or more extremities necessitates the use of a convoluted set of codes, but for the first time, all four limbs are compensated. The base code, which should represent the leg with the most muscles injected, is the first code. Choose between 64642 chemodernervation of one extremity with 1 to 4 muscle(s) or 64644 chemodenervation of one extremity with 5 or more muscle(s) (s). Add-on codes for additional limb injections are based on the amount of muscles injected in each limb. There are no modifiers required. Use +64643 for each additional extremity injected with 1 to 4 muscle(s), and +64645 for each additional limb injected with 5 or more muscles.

The erector spinae/paraspinal muscles and the rectus abdominis/obliques were previously regarded to be part of a limb injection, but trunk muscles are now considered a distinct region that contains the erector spinae/paraspinal muscles and the rectus abdominis/obliques. When injecting 1 to 5 muscles, use CPT code 64646, and when injecting 6 or more muscles, use CPT code 64647. Per session, each code can only be used once. Muscles like the trapezius, rhomboid, gluteus, and piriformis would be considered limb muscles based on the site definition above.

Modifiers. Modifiers for right and left-sided injections are allowed by some insurance carriers. To find out when to bill with a modifier, check with your local carriers. When a code appears on a billing sheet for the second time without a modifier, it is usually flagged as a duplication. Modifiers do not apply to some codes, such as 64611 and 64615, because they can only be used once each injection session. A list of modifiers can be found in table 3.

Anatomical Guidance is a term used to describe how a person’s For many injection sites, electrophysiologic or visual assistance is recommended to assure efficacy and safety. Electromyography, muscular stimulation, and ultrasound can all be utilized separately or in combination depending on the clinical situation. Electromyography or electrical stimulation can be performed under ultrasound supervision, for example, according to Medicare. These procedures are reimbursable because they maximize clinical efficacy. The CPT codes for BTX injections under anatomic guidance are listed in Table 4. Per injection session, each code can only be used once.

MARCH 2014 PRACTICAL NEUROLOGY 25 REIMBURSEMENT AND EXPECTED COLLECTIONS

Understand your primary regional botulinum toxin insurance policies. This will aid in the reduction of payment delays and even denials. Before the patient’s next injection cycle, double-check each claim to make sure the procedure, anatomic guidance, and medicine were all reimbursed in accordance with your payer contract. In most cases, the insurance company will only pay for procedures that are deemed medically essential. When a payer pays a code bilaterally, the reimbursement for the second side is usually cut in half. Billing and coding, insurance verification, local coverage policy assistance, and claims denials and appeals are all handled by reimbursement specialists at each of the major businesses.

This page is solely meant to serve as a guide. To guarantee compliance with current policies and laws, please refer to current policies for carriers in your area and/or CMS. Specific questions should be directed to the appropriate carrier.

Dr. Taylor is a neurologist in private practice in Columbus, Ohio, as well as a Clinical Associate Professor of Neurology at Ohio University College of Osteopathic Medicine in Athens, Ohio.

  • CPT 2014; Standard Edition, American Medical Association Current Procedural Terminology.
  • Full prescribing information for Botox (onabotulinumtoxinA). Allergan, Inc., Irvine, CA; 2013.
  • Ipsen Biopharm Ltd., Wrexham, UK, 2012. Dysport (abobotulinumtoxinA) Full Prescribing Information.
  • Full Prescribing Information for Myobloc (rimabotulinumtoxinB) Louisville, KY: Solstice Neurosciences, LLC; 2010.
  • Full prescribing information for Xeomin (incobotulinumtoxinA). Merz Pharmaceuticals, LLC, Greensboro, NC; August 2011.

What insurance do I need to inject Botox?

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