If you have periodontal disease, your dentist will most likely recommend scale and root planing (also known as “deep cleanings”) to remove plaque and tartar from the affected teeth’s roots. This treatment aids in the reduction of bacterial counts, as well as the reduction of inflammation and pocket depths. Arestin is an antibiotic that can be used to improve the effectiveness of scaling and root planing.
Arestin includes microspheres, which are invisible to the naked eye and smaller than a grain of sand.
The antibiotic minocycline hydrochloride is used to fill the microspheres. They gradually release the antibiotic, killing germs and allowing your gums to heal more quickly than scaling and root planing alone. This type of antibiotic differs from pills in that it is injected directly into the pocket where it is needed, delivering a considerably higher concentration of antibiotic to that region than a pill can.
Arestin is packaged in small cartridges that are inserted into a syringe-like device that softly expresses the microspheres beneath the gumline. After scaling and root planing, or after routine maintenance visits, it can be administered to the pocket. Arestin dissolves on its own in the pocket, therefore it is not essential to remove it.
If a patient has a known allergy to minocycline or tetracyclines, arestin should be avoided.
Arestin belongs to the tetracycline antibiotic family.
Tetracylclines have been linked to persistent tooth discolouration in children.
As a result, Astin should not be used in youngsters or women who are pregnant or nursing.
Arestin costs vary per office and are determined by the number of teeth and pockets involved. Each pocket larger than 5mm requires one dose and is treated as a single site. Arrestin may be required at six different places on each tooth. The majority of dentists charge between $45 and $85 per location. As you can see, the price of Arestin can be quite high.
Arestin is used in my office at maintenance visits to treat pockets that remain after scaling and root planing.
Because there are fewer spots or deep pockets to treat, the cost of treatment is considerably reduced. We also participate in Arestin Rx Access, a program that allows our patients with medical insurance to have Arestin covered by their pharmacy plan. On behalf of the patient, a prescription is submitted. Their insurance company deducts the cost, and a supply of Arestin is sent to our office for the patient’s next appointment. The Arrestin is administered for a nominal price. Regardless of the number of sites involved, there is only one cost each hygiene visit.
What are the possible side effects of Arestin?
If you have a side effect that bothers you or does not go away, tell your doctor.
These aren’t all of Arestin’s possible negative effects. Ask your doctor or pharmacist for more information.
For medical advice on side effects, contact your doctor. You can contact the FDA at 1-800-FDA-1088 to report side effects.
DESCRIPTION
ARESTIN (minocycline hydrochloride) microspheres, 1mg is a professional subgingival sustained-release product containing the antibiotic minocycline hydrochloride incorporated into a bioresorbable polymer, Poly (glycolide-co-dl-lactide) or PGLA, for subgingival administration into periodontal pockets. Each unit-dose cartridge contains 1 mg of minocycline free base in the form of minocycline hydrochloride.
Minocycline hydrochloride has the chemical formula C23H27N3O7 HCl and a molecular weight of 493.94. Minocycline hydrochloride has the following structural formula:
Is there a generic for Arestin?
In the United States, there is currently no therapeutically equivalent form of Arestin available.
Note: Scammers may try to offer an illegal generic version of Arestin through the internet. These medications could be fakes, which could be dangerous. If you buy drugs online, make sure you’re dealing with a reliable and legitimate company. If you have any concerns about purchasing medications online, seek counsel from your health care professional.
How long does Arestin stay in the pocket?
ARESTIN stays in the pocket for at least 14 days, ensuring that your dental professional may continue to treat you. ARESTIN is also safe and simple to use. 1) Don’t touch anything. Avoid touching the parts of your gums that have been treated by the dentist. 2) Hold off on brushing.
How long does it take for Arestin to take effect?
ARESTIN (minocycline HCl) Microspheres, 1 mg fights infection by targeting periodontal bacteria. Results were seen at 1 month when incorporated into a standard oral care regimen with scaling and root planing (SRP), with pocket depth reduction seen at 3 months and maintained at 9 months.
Can Arestin fall out?
Arestin (minocycline HCl 1mg) microspheres are a treatment for chronic periodontitis, a gum infection that can lead to tooth loss and is associated to other major disorders like heart disease, osteoporosis, and diabetes. Arestin employs cutting-edge microsphere technology to eliminate periodontal disease-causing bacteria quickly and effectively.
When bacteria builds up on your teeth beneath the gums, periodontal disease develops, causing your gums to become red and inflamed. If left untreated, inflammation causes damage to the ligaments and bone that hold your teeth in place, resulting in pockets around your teeth.
Your teeth may become loose and fall out as the condition develops and these pockets deepen. By evaluating pocket depth and studying patient x-rays, dentists and licensed dental hygienists can determine the severity of a patient’s periodontitis.
Arestin is a locally administered antibiotic that is injected directly into the diseased spaces between your teeth. After scaling and root planing, a typical procedure used to treat periodontal disease, a dentist or dental hygienist can inject Arestin.
Arestin, when used with scale and root planing, helps to minimize the depth of infected pockets and slow disease progression. Arestin with scaling and root planing is more effective than scaling and root planing alone in combating periodontal disease. Arestin has been demonstrated to be especially successful in patients who are more difficult to treat, such as smokers or those with cardiovascular disease.
At 22 universities and dentistry schools across the country, Arestin was studied in over 920 patients with adult periodontitis. These massive clinical trials enabled for the collecting of a lot of information about Arestin’s safety and efficacy. There were few adverse effects reported, and those that were were equivalent to placebo. Arestin did not change taste buds, discolor teeth, or produce stomach trouble in these studies.
The Arestin Facts
- Treatment with Arestinâ (minocycline HCl 1mg) microspheres is quick, simple, and painless.
- Using Arestin and scaling and root planing to treat periodontal disease today may help you keep your teeth tomorrow.
- Arestin is bioadhesive and bioresorbable, which means it will not leak or fall out, leaving nothing for the dentist or hygienist to remove during a follow-up visit.
- Arestin with SRP treatment for periodontal disease can help keep gum pockets below the surgical intervention threshold.
Arestin FAQs
1. Who can ArestinTM(minocycline HCl 1mg) help?
Arestin can help the majority of people with periodontal disease. Arestin, on the other hand, should not be used on youngsters or women who are pregnant or breastfeeding.
2. Is Arestin therapy a new procedure?
It is not a novel concept to employ a locally given antibiotic. Antibiotics have been used in conjunction with scaling and root planing treatment by dentists for years. Arestin, on the other hand, is the first time-released antibiotic encapsulated in microspheres that may be injected locally. Arestin contains microspheres, which make it a quick, painless treatment that works better than SRP alone.
3. Is Arestin effective?
Yes, Arestin combined with scaling and root planing is a more effective periodontal disease treatment than scaling and root planing alone. In clinical tests, individuals who received a combination of scaling and root planing and Arestin had healthier gums and pockets than those who only received scaling and root planing.
4. How long does Arestin treatment take?
In clinical testing, researchers were able to treat 30 periodontal pockets on average in under ten minutes. In one minute, you can visit up to three different websites! Treatment time for placement varies depending on the location and number of periodontal pocket sites, but it is normally a quick, painless, and comfortable treatment.
5. Will I need to see the dentist again to have Arestin removed?
No. Arestin doesn’t need to be bandaged, and it won’t leak or fall out. It is absorbed by the body naturally and does not need to be removed by your dentist.
6. Is Arestin therapy painful?
Arestin is a simple treatment that causes no discomfort. There was no need for anesthesia in clinical trials, which means no needles.
7. Are there any negative consequences?
There were very minor negative effects documented in clinical investigations. Those reported were comparable to those in the placebo group. Arestin has no effect on taste buds, does not discolor teeth, and does not induce stomach trouble.
8. What is Arestin’s price?
The cost of Arestin treatment varies depending on your specific treatment requirements. After your dentist has assessed your dental health and discussed treatment choices with you, he or she can give you a cost estimate. Remember that treating your gum disease now is less expensive and healthier for your health than waiting until symptoms have progressed.
Why Use an Antibiotic?
Periodontal disease is a bacterial infection that can be treated with antibiotics, as can most bacterial illnesses. Scaling and root planing is a technique used by dentists and hygienists to treat periodontal disease (SRP). SRP is a non-surgical procedure that involves a deep cleaning above and below the gum line to eliminate plaque from the teeth.
The root is then planed until it is smooth to remove bacteria-breeding plaque deposits on the root. SRP is successful in removing plaque buildup, however it does not eradicate all of the germs that cause periodontal disease. The use of Arestin (minocycline HCl 1 mg) aids in the elimination of any residual bacteria.
In the treatment of periodontal infection, locally administered antibiotics (LAAs) play a crucial role. Antibiotics kill germs in periodontal pockets when they are administered directly into the diseased area. Arestin (minocycline HCl 1 mg) microspheres contain the antibiotic minocycline, which has been demonstrated to be particularly efficient in removing the germs that cause periodontitis.
Effective in Clinical Trials
Arestin (minocycline HCl 1 mg) microspheres underwent extensive and well-controlled clinical trials. More than 920 patients with adult periodontitis were studied at 22 universities and dentistry schools across the United States.
Patients who received Arestin with scaling and root planing (SRP) had considerably less pocket depth than those who received SRP alone in these clinical trials. Pocket depth is a parameter used to diagnose and evaluate periodontal disease severity. When supporting tissue and bone are removed, pockets occur around teeth.
The lowering of pocket depth is a desired goal in periodontal disease treatment since the severity of periodontal disease is determined in part by the depth of pockets. Furthermore, scientific investigations revealed that patients treated with a combination of Arestin and SRP reduced their pocket depth below 5mm by 25% more than those treated with SRP alone, returning their dental health to a more manageable level.
Arestin combined with SRP was also found to be particularly effective in patients with cardiovascular disease and smokers in the trials. Arestin was also successful in more difficult-to-treat teeth, such as molars, and in difficult-to-treat areas known as furcations, which develop between tooth roots. Because of their shape and placement in the mouth, molar teeth and their furcation sites are notoriously difficult to clean with the scaling and root planing technique.
Arestin is simple to use, allowing dentists to reach these difficult-to-treat areas. Because Arestin is so adhesive, it stays in these hard-to-treat areas for a long time, killing the infection. Arestin can be given directly after scaling and root planing, allowing patients to get all of their oral health needs taken care of in one visit.
Furthermore, studies have found a link between periodontal infection and cardiovascular disease, diabetes, osteoporosis, and an increased risk of pre-term, low-birth-weight kids. Because of these increased risks, early detection and treatment of periodontal disease is even more critical.
Tips After Treatment
Following treatment for periodontal disease with a combination of Arestin and scaling and root planing (SRP), you should keep your gums and mouth healthy by brushing three times a day and flossing on a regular basis. Patients should refrain from consuming hard, crunchy, or sticky foods for one week after therapy. After 12 hours, you can resume your normal dental hygiene routine. Speak with your dentist and follow these advice to get the best benefits from your treatment.
Follow the guidelines given by your dental professional to get the greatest outcomes. These key guidelines will also come in handy:
- Wait ten days before using floss, toothpicks, or other interdental cleaning equipment.
Gum disease can return, therefore it’s important to have it checked on a regular basis. Please remember to attend your follow-up visits.
When is the best time to place Arestin?
Following a scaling and root planing (SRP) procedure, ARESTIN is given to diseased areas in the gums. ARESTIN may be applied at the same time as your SRP or at a later date by your dental expert.
Can I drink alcohol with Arestin?
It’s vital that the Arestin stays in place, as cleaning between the treated areas will prematurely remove the gel. For at least 7 days after Arestin is implanted, avoid consuming hard, sticky, chewy, or crunchy foods. For a minimum of 48 hours, do not smoke or consume alcoholic beverages.
Can pockets in gums heal?
Periodontal pockets are gaps or openings beneath the gum line that surround the teeth. Infection-causing microorganisms can accumulate in these areas.
Periodontal pockets are a sign of periodontitis (gum disease), a dangerous infection of the gums.
Periodontal pockets can be treated and reversed with proper oral hygiene and dental care. Periodontal pockets, on the other hand, if left untreated, can lead to tooth loss.
Continue reading to learn more about periodontal pockets, as well as treatment options, prevention, and risk factors that you can manage.